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Bei Bei (Jenny) Guo

Associate Professor

Department of Experimental Statistics

Room 61 M. D. Woodin Hall
Telephone: 225-578-7181
Email: beibeiguo@lsu.edu

Publications:

Statistical Methodology

· Guo, B., Zang, Y. (2021). BILITE: A Bayesian Phase II Design for Immunotherapy by Jointly Modeling the Longitudinal Immune Response and Time-to-event Efficacy. Statistics in Medicine, In Press.

· Guo, B., Garrett, L., and Liu, S. (2021). A Bayesian Phase I/II Design for Clinical Trials Combining an Immunotherapeutic Agent with a Chemotherapeutic Agent. Journal of the Royal Statistical Society: Series C, In Press.

· Guo, B. and Liu, S. (2020). An optimal Bayesian predictive probability design for phase II clinical trials with simple and complicated endpoints. Biometrical Journal, In Press.

· Zang, Y., Guo, B., Han, Y., Cao, S., Zhang, C. (2019). A Bayesian adaptive marker-stratified design for molecularly targeted agents with customized hierarchical modeling. Statistics in Medicine, (38): 2883-2896.

· Guo, B., Park, Y., and Liu, S. (2019). A Utility-based Bayesian phase I/II Design for immunotherapy trials with progression-free survival endpoint. Journal of the Royal Statistical Society: Series C, (68): 411-425.

· Guo, B., Zang, Y. (2019). A Bayesian Adaptive Phase II Clinical Trial Design Accounting for Spatial Variation. Statistical Methods in Medical Research, (28): 3187-3204.

· Guo, B., Li, D., and Yuan, Y. (2018). SPIRIT: A Seamless Phase I/II Randomized Design for Immunotherapy Trials. Pharmaceutical Statistics, (17): 527-540.

· Liu, S., Guo, B., and Yuan, Y. (2018). A Bayesian Phase I/II Trial Design for Immunotherapy. Journal of the American Statistical Association, (113): 1016-1027.

· Dale, R., and Guo, B. (2018). Estimating epidemiological parameters of a stochastic differential model of HIV dynamics using hierarchical Bayesian statistics. PLOS ONE. 13(7):e0200126. doi: 10.1371/journal.pone.0200126

· Zang, Y. and Guo, B. (2018). Optimal two-stage enrichment design correcting for biomarker misclassification. Statistical Methods in Medical Research, (27): 35-47.

· Guo, B. and Liu, S. (2017). Optimal Benchmark for Evaluating Drug-combination Dose-finding Clinical Trials. Statistics in Biosciences, 10(1): 184-201.

· Guo, B. and Yuan, Y. (2017). Bayesian Phase I/II Biomarker-based Dose Finding for Precision Medicine with Molecularly Targeted Agents. Journal of the American Statistical Association, (112): 508-520.

· Guo, B. and Yuan, Y. (2017). A comparative review of methods for comparing means using partially paired data. Statistical Methods in Medical Research, 26(3): 1323-1340.

· Yuan, Y., Guo, B., Munsell, M., Lu, Karen, Jazaeri, A. (2016). MIDAS: a practical Bayesian design for platform trials with immunotherapy agents. Statistics in Medicine, (22): 3892-3906.

· Zang, Y. and Guo, B. (2016). Two-stage methods to implement and analyze the biomarker-guided clinical trial designs in the presence of biomarker misclassification. Precision Medicine, 2: e1230. doi: 10.14800/pm.1230.

· Guo, B., Zang, Y., and Yuan, Y. (2015). A Bayesian phase I/II clinical trial design in the presence of informative dropouts. Statistics and Its Interface, (8): 217-226.

· Guo, B. and Yuan, Y. (2015). A Bayesian dose-finding design for phase I/II clinical trials with non-ignorable dropouts. Statistics in Medicine, (34): 1721-1732.

· Guo, B., Li, Y. and Yuan, Y. (2015). A dose-schedule-finding design for phase I/II clinical trials. Journal of the Royal Statistical Society: Series C, (65): 259-272.

· Guo, B. and Li, Y. (2015). Bayesian dose-finding designs for combination of molecularly targeted agents assuming partial stochastic ordering. Statistics in Medicine, (34): 859-875.

· Guo, B. and Li, Y. (2014). Bayesian designs of phase II oncology trials to select maximum effective dose assuming monotonic dose-response relationship. BMC Medical Research Methodology, 14:95.

· Guo, B., Villagran, A., Vannucci, M., Wang, J., Davis, C., Man, T., Lau, C. and Guerra, R. (2010). Bayesian estimation of genomic copy number with single nucleotide polymorphism genotyping arrays. BMC Research Notes, 3:350.

Interdisciplinary Research

· Zhang, Z., Sun, C., Guo, B., (2021). Transfer-Learning Guided Bayesian Model Updating for Damage Identification Considering Modeling Uncertainty. Mechanical Systems and Signal Processing. In press.

· Xie, Y., Guo, B., Zhang, R. (2021). Cost-Effectiveness Analysis of Radiotherapy Techniques for Whole Breast Irradiation. PLOS ONE. In press.

· Xie, Y., Guo, B., Zhang, R. (2020). Cost-effectiveness analysis of advanced radiotherapy techniques for post-mastectomy breast cancer patients. Cost Effectiveness and Resource Allocation. In Press

· Xie, Y., Bourgeois, D., Guo, B., Zhang, R. (2020). Comparison of conventional and advanced radiotherapy techniques for left-sided breast cancer after breast conserving surgery. Medical Dosimetry. In Press.

· Pandey, A., Yoganathan, A., Guo, B., Zhang, R. (2019). Feasibility of generating synthetic CT from T1-weighted MRI using a linear mixed-effects regression model. Biomedical Physics & Engineering Express. In Press.

· Xie, Y., Bourgeois, D., Guo, B., Zhang, R. (2019). Post-mastectomy radiotherapy for left-sided breast cancer patients: comparison of advanced techniques. Medical Dosimetry. In Press.

· Bakhit, P., Osman, O., Guo, B., Ishak, S. (2018). A Distraction Index for Quantification of Driver Eye Glance Behavior: A Study Using SHRP2 NEST Database. Journal of Safety Science.

· Zhang, R., Heins, D., Sanders, M., Guo, B., Hogstrom, K. (2018). Evaluation of a mixed beam therapy for post-mastectomy breast cancer patients: bolus electron conformal therapy combined with intensity modulated photon radiotherapy and volumetric modulated photon arc therapy. Medical Physics. DOI: 10.1002/mp.12958.

· Bakhit, P., Guo, B., Ishak, S. (2018). Crash and Near-Crash Risk Assessment of Distracted Driving and Engagement in Secondary Tasks: A Naturalistic Driving Study. Journal of the Transportation Research Board. DOI: 10.1177/0361198118772703.

· Heppner, W., Spears, C., Fernandez, V., Castro, Y., Li, Y., Guo, B., Reitzel, L., Vidrine, J., Mazas, C., Woerpel, L., Cinciripini, P., Ahluwalia, J., Wetter, D. (2016). Dispositional Mindfulness Predicts Enhanced Smoking Cessation and Smoking Lapse Recovery. Annals of Behavioral Medicine. (50) 337-347.

· Xu, W., Chafi, H., Guo, B., Heymsfield, S., Murray, K. Zheng, J., Jia, G. (2016). Quantitative Comparison of Two Dual-Energy X-ray Absorptiometry (DXA) Systems in Assessing Body Composition and Bone Mineral Measurements. Journal of Clinical Densitometry. 19(3) 298-304.

· Chafi, H., Elias, S., Nguyen, H., Friel, H., Knopp, M., Guo, B., Heymsfield, S., Jia, G. (2015). Effect of parallel radiofrequency transmission on arterial input function selection in dynamic contrast-enhanced 3 Tesla Pelvic MRI. Journal of Magnetic Resonance Imaging, (43) 229-235.

· Shah, Z., Elias, S., Abaza, R., Zynger, D., DeRenne, L., Knopp, M., Guo, B., Schurr, R., Heymsfield, S., Jia, G. (2015). Performance Comparison of 1.5-T Endorectal Coil MRI with 3.0-T Nonendorectal Coil MRI in Patients with Prostate Cancer. Academic Radiology, 22(4) 467-474.

Other publications

· Zang, Y. and Guo, B. (2016) Enrichment design accommodating the biomarker misclassification. Atlas of Science, March 13, 2016.

· Guo, B. and Zhang, R. (2018). Statistical Methods for Clinical Trial Designs in the New Era of Cancer Treatment. Biostatistics and Biometrics Open Access Journal, 5(3).

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